One creative attempt to estimate how widespread such dishonesty really is involves comparisons between fields of varying “hardness.” The author, Daniele Fanelli, theorized that the farther from physics one gets, the more freedom creeps into one’s experimental methodology, and the fewer constraints there are on a scientist’s conscious and unconscious biases. If all scientists were constantly attempting to influence the results of their analyses, but had more opportunities to do so the “softer” the science, then we might expect that the social sciences have more papers that confirm a sought-after hypothesis than do the physical sciences, with medicine and biology somewhere in the middle. This is exactly what the study discovered: A paper in psychology or psychiatry is about five times as likely to report a positive result as one in astrophysics. This is not necessarily evidence that psychologists are all consciously or unconsciously manipulating their data—it could also be evidence of massive publication bias—but either way, the result is disturbing.
http://www.firstthings.com/article/2016/05/scientific-regress